LEVITRA AND OTHER SUBSTANCES
LEVITRA AND GRAPEFRUIT
Numerous reports and consecutive studies have shown that it's better to avoid taking grapefruit and grapefruit juice for men who are using erectile dysfunction medications such as Viagra, Cialis or Levitra. Moreover, recent studies suggest that not only grapefruit should be avoided by ED patients as tangelos, Seville oranges and limes also make part of the “not to be used with” list.
Why grapefruit and similar fruits are not to be mixed with Levitra and other ED medication, you might ask? Grapefruit and its juice are known to be very active in what concerns interacting with active elements of more types of drug, not just PDE-5 inhibitors. It is well known that doctors suggest patients cutting grapefruits and similar fruits from their regimens when taking antidepressants, blood pressure medications, cholesterol level drugs, HIV drugs and numerous other substances. Fruits, which are similar to grapefruit in their chemical content include limes, tangelos and Seville oranges. Ordinary oranges and other citrus fruits are safe in that sense and do not interact with medications, so you can consume them just as much as you do on a regular basis.
It is better for you to take these suggestions seriously as mixing Levitra with grapefruit containing products may alter the drug's effects and make it work less efficiently as you would expect. It contains such chemicals as naringin, bergamottin and dihydroxybergamottin that posses protein inhibiting properties, which increase the absorption abilities of many drugs. In other words, grapefruit and products such as grapefruit juice increase the chemical activity of numerous medications, which may lead to actual overdose situations even if the safe amount of the drug pill-wise was not exceeded. This typically leads to manifestation of the drug's side-effects that otherwise would be suppressed because of the smaller quantities of the drug's active elements absorbed by the body itself.
These properties of grapefruit were observed in the late 1980's when several cases of lethal overdose have taken place. Detailed studies have concluded that grapefruit and grapefruit juice consumption was the cause for such tragic outcomes to take place.
If you have taken grapefruit together with Levitra and suspect to have an overdose, pay attention to the symptoms you may be experiencing. The typical symptoms of Levitra overdose include vision problems, back and muscle pain. So if you experience any of the mentioned conditions you should seek medical assistance as soon as possible.